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Interestingly, inhibiting DDAH reduces TGF-/Smad-mediated collagen synthesis in fibroblasts and limits alveolar type II (ATII) cell proliferation in an ADMA-dependent manner [81, 84]

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Additionally, histopathological examination of pancreatic tissue from animal models of AP confirmed that vitamin E could reduce pancreatic tissue edema, inflammatory cell infiltration, and acinar cell necrosis (126)

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